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The Detroit Tigers (43-24) travel to play the Baltimore Orioles (26-38) to begin a three-game series on Tuesday. The Orioles have dropped two of their past three games, falling 5-1 to the Oakland Athletics in their previous matchup. Meanwhile, the Tigers took two out of three games versus the Chicago Cubs in their last series. Brant Hurter is scheduled to start for Detroit, while Cade Povich is on the hill for Baltimore. 

First pitch from Oriole Park at Camden Yards is set for 6:35 p.m. ET. Baltimore is a -134 favorite on the money line (risk $134 to win $100) in the latest Tigers vs. Orioles odds from FanDuel Sportsbook, while the over/under for total runs scored is 9. Before making any Tigers vs. Orioles picks, be sure to see the MLB predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 12 of the 2025 MLB season on a 27-23 run on top-rated MLB sides picks. It has excelled making home run prop picks, returning more than 35 units of profit over the past two months. Anybody following at sportsbooks and on betting apps could have seen strong returns.

Now, the model has set its sights on Tigers vs. Orioles and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Here are several MLB odds and betting lines for Tigers vs. Orioles, which you can get in on with a DraftKings promo code or a FanDuel promo code.

Tigers vs. Orioles money line

Baltimore -134, Detroit +113 at FanDuel

Tigers vs. Orioles over/under

9 runs

Tigers vs. Orioles run line 

Baltimore -1.5 (+155)

Tigers vs. Orioles picks

See picks at SportsLine

Tigers vs. Orioles streaming 

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Why the Tigers can win

First baseman Spencer Torkelson has been a solid run producer for the Tigers. He's currently tied for 12th in the majors in home runs (15) and tied for 10th in RBI (45). The 25-year-old has logged a hit in three straight games, including going 2-of-4 with a double and two runs driven in in his last contest. 

Left fielder Riley Greene is another reliable hitter. He's first on the team in batting average (.276) and hits (69). In addition, Greene has 13 home runs and 44 RBI. In Sunday's win over the Cubs, he went 2-of-4 with two runs driven in. See which team to back at SportsLine.

Why the Orioles can cover

Right fielder Ryan O'Hearn is tied for ninth in the MLB in batting average (.316) while leading the team in OBP (.397) and hits (60). The 31-year-old also has nine home runs and 24 RBI. In his previous outing, O'Hearn was 1-of-4 with a single and an RBI. 

Shortstop Gunnar Henderson has plus power and a a solid eye for contact. Thus far in the 2025 season, he's batting .265 with eight dingers and 17 RBI. On June 7 against the Athletics, Henderson went 3-of-4 with an RBI and one run scored. This was his third game of the month with two-plus hits. See which team to back at SportsLine

How to make Tigers vs. Orioles picks

SportsLine's model is leaning Under on the total, projecting 8.8 combined runs, and it says one side of the money line has all the value. You can head to SportsLine to see the model's MLB picks

So who wins Tigers vs. Orioles, and which side of the money line has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.